DNA Methylation as a Long-term Biomarker of Exposure to Tobacco Smoke

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Most biomarkers of exposure tend to have short half-lives. This includes cotinine, a metabolite of nicotine widely used to assess smoke exposure. Cotinine is thus unsuitable as a determinant of past exposure to cigarette smoke. Dr. James Flanagan, Faculty of Medicine, Department of Surgery & Cancer, Imperial College, Lo…

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