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Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis

Neutrophils play an active role in protecting cartilage from damage by dispatching microvesicles (MVs) to do their bidding in this tissue they otherwise cant access. Mauro Perretti discusses suggesting that immune cells can provide protection against tissue degradation in inflammatory arthritis and that the MVs may be manipulated to deliver therapeutics to diseased joints.

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