Real-time imaging of apoptosis in patients with glaucoma

Retinal cell apoptosis occurs in many ocular neurodegenerative conditions including glaucoma—the major cause of irreversible blindness worldwide. Using a new imaging technique called DARC (detection of apoptosing retinal cells) researchers assess if annexin 5 labelled with fluorescent dye DY-776 could be used safely in humans to identify retinal cell apoptosis.

Professor Cordeiro is Chair and Professor of Ophthalmology at Imperial College London, Honorary Consultant Ophthalmologist and Research Lead at the Western Eye Hospital, Imperial College Healthcare NHS Trust.

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