Clonal Expansion of Infected CD4+ T Cells in People Living with HIV

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Clonal Expansion of Infected CD4+ T Cells in People Living with HIV

Clonal Expansion of Infected CD4+ T Cells in People Living with HIV

John Coffin

Tufts University

HIV infection is not curable with current antiretroviral therapy (ART) because a small fraction of CD4+ T cells infected prior to ART initiation persists. Understanding the nature of this latent reservoir and how it is created is essential to development of potentially curative strategies. John Coffin discusses.

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