The secretory granule protein secretogranin-2 is processed to the bioactive neuropeptide secretoneurin. While these are expressed in hypothalamic neurons and anterior pituitary cells, a role in hormonal control of reproduction is unknown. Vance L. Trudeau discusses in vivo evidence that secretogranin-2 plays critical roles in fertility regulation. Image courtesy of Vance L. Trudeau.
Image courtesy of interviewee. May 3, 2021