DNA-driven condensation assembles the meiotic DNA break machinery

The accurate segregation of chromosomes during meiosis relies on homologous recombination initiated by DNA double-strand breaks (DSBs) made by the Spo11 protein. Corentin Claeys Bouuaert discusses this through the molecular characterization of Saccharomyces cerevisiae RMM (Rec114, Mei4 and Mer2) proteins.

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