Browsing Category
Clinical Microbiology
Integrated pathogen load and host-pathogen interactions in severe malaria
The pathogenesis of infectious diseases depends on the interaction of host and pathogen. In Plasmodium falciparum malaria, host and parasite…
Cholesterol and inflammasome activation
Cellular lipids determine membrane integrity and fluidity and are being increasingly recognized to influence immune responses. Cellular cholesterol…
Facing Down Emerging Viruses
The Ebola epidemic in West Africa has highlighted the threat of newly emerged viral infections. Michal Barski discusses…
Cancer stem cells in squamous cell carcinoma switch between two distinct phenotypes
Cancer stem cells (CSC) that maintain and initiate tumors have also been implicated in invasion and metastasis, but…
Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis
Neutrophils play an active role in protecting cartilage from damage by dispatching microvesicles (MVs) to do their bidding…
The Resolution of Inflammation
Mauro Perretti and his research team pioneered the concept that acute inflammation resolves, naturally, by the engagement of…
Do trypanosome turncoats wait before they commit?
Gloria Rudenko, Wellcome Senior Research Fellow in the Basic Biomedical Sciences Reader in Molecular Microbiology, Wellcome Trust/ Imperial…
Target of Rapamycin and developmental mTORopathies
The Bordey Lab has been focused on the mammalian Target of Rapamycin, mTOR. mTOR is a converging point…
Reflecting On The End Of The Ebola Epidemic
John Oxford discusses the origins of the 2014 Ebola epidemic, the index case, investigation and identification of the…
Cell-line authentication: End the scandal of false cell lines
Cell-line misidentification is a continuing problem, with an estimated 15% or more of human cell lines not being…