Clinical Microbiology

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Integrated pathogen load and host-pathogen interactions in severe malaria

Imperial College London

The pathogenesis of infectious diseases depends on the interaction of host and pathogen. In Plasmodium falciparum malaria, host and parasite processes can […]

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Cholesterol and inflammasome activation
Imperial College London
Biology Professional

Cellular lipids determine membrane integrity and fluidity and are being increasingly recognized to influence immune responses. Cellular cholesterol requirements are […]
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Facing Down Emerging Viruses
Imperial College London
Biology Professional

The Ebola epidemic in West Africa has highlighted the threat of newly emerged viral infections. Michal Barski discusses why and […]
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Cancer stem cells in squamous cell carcinoma switch between two distinct phenotypes
Queen Mary, University of London
Cancer Professional

Cancer stem cells (CSC) that maintain and initiate tumors have also been implicated in invasion and metastasis, but whether EMT […]
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Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis
Barts and the London
Chemistry Professional

Neutrophils play an active role in protecting cartilage from damage by dispatching microvesicles (MVs) to do their bidding in this […]

The Resolution of Inflammation
Barts and the London
Chemistry Professional

Mauro Perretti and his research team pioneered the concept that acute inflammation resolves, naturally, by the engagement of endogenous mediators […]
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Do trypanosome turncoats wait before they commit?
Imperial College London
Biology Professional

Gloria Rudenko, Wellcome Senior Research Fellow in the Basic Biomedical Sciences Reader in Molecular Microbiology, Wellcome Trust/ Imperial College Ooi […]

Target of Rapamycin and developmental mTORopathies
Yale University
Clinical Microbiology Professional

The Bordey Lab has been focused on the mammalian Target of Rapamycin, mTOR. mTOR is a converging point in cell […]
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Reflecting On The End Of The Ebola Epidemic
Queen Mary University of London
Clinical Microbiology Professional

John Oxford discusses the origins of the 2014 Ebola epidemic, the index case, investigation and identification of the Ebola virus.
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Cell-line authentication: End the scandal of false cell lines
University College London
Clinical Microbiology Professional

Cell-line misidentification is a continuing problem, with an estimated 15% or more of human cell lines not being derived from […]
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