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Novel miRNAs and their Target Gene Networks from Hippocampi of Rats that Performed Regular Exercise

Key Question Being Explored in This Insight:

MicroRNAs (miRNAs) have been previously described to regulate gene expression. To determine whether such non-coding RNA regulates gene activities in the brain as a consequence of regular exercise, expressed sequence tags (ESTs) identified in a related study by one of the authors on the hippocampi of Swiss Wistar rats that exercised on a treadmill were subjected to an in silico analysis. Marla A. Endriga discusses new insights to the well-established salutary effects of physical activity on learning and memory.

Institution: University of the Philippines

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MicroRNAs (miRNAs) have been previously described to regulate gene expression. To determine whether such non-coding RNA regulates gene activities in the brain as a consequence of regular exercise, expressed sequence tags (ESTs) identified in a related study by one of the authors on the hippocampi of Swiss Wistar rats that exercised on a treadmill were subjected to an in silico analysis. Marla A. Endriga discusses new insights to the well-established salutary effects of physical activity on learning and memory.

Image courtesy of interviewee. January 12, 2023

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