Role of CCL7 in Experimental Allergic Conjunctivitis

Molecules that are necessary for ocular hypersensitivity reactions include the receptors CCR1 and CCR3; CCL7 is a ligand for these receptors. Santa Ono discusses the role of CCL7 in mast cell activity and motility in vitro and investigated the requirement for CCL7 in a murine model of IgE-mediated allergic conjunctivitis.

Photo credit: Paul Joseph / UBC Brand and Marketing

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