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Role of sodium/calcium exchange in heart failure-induced arrhythmias

Sudden death from ventricular arrhythmias is an important source of mortality in patients with congestive heart failure. Rapid ventricular arrhythmias also occur in small animal models of heart failure. Prolongation of the action potential in failing hearts is thought to be an important arrhythmia mechanism.

 

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Mechanisms of calcium transient and action potential alternans in cardiac cells and tissues

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