Transcription factor 7-like 1 and hypothalamic pituitary axis development

The relevance of transcription factor 7-like 1 (TCF7L1) during hypothalamo–pituitary (HP) axis development remains unknown. Carles Gaston-Massuet discusses how TCF7L1 acts as a transcriptional repressor to regulate the expression of the hypothalamic signals involved in pituitary formation. 

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